Sentence examples for mediating the suppression from inspiring English sources

The possible physiological role of this regulatory mechanism and the specific molecules mediating the suppression remain to be determined.

Moreover, Bmi1 is also important for self-renewal of post-natal NSCs, mediating the suppression of the Ink4/Arf cell cycle inhibitor proteins, p16 and p19.

A subpopulation of plasmacytoid DCs derived from monocytes expressing CD123hi/CCR6+/IDO+ that are responsible for mediating the suppression of effector T cells has recently been described.

Because IL13Rα2 functions as a decoy receptor of IL-13 signaling, we hypothesized that a subset of critically important genes mediating the suppression of lung metastases are controlled by this signaling cascade.

Jung et al. (abstract 565) studied effects of the short-chain fatty acid butyrate, found in dairy products and known to inhibit histone deacetylases such as that mediating the suppression of PPARγ function by tumor necrosis factor-α.

DC-derived IL-12 may be involved in mediating the suppression of Treg cells because IL-12 plays a major part in promoting Th1 responses that inhibit Treg cell generation [ 22, 23].

It implies that the activation of AMPK and JNK pathways mediates the suppression of carboxylesterases by metformin.

After dissection and transplantation, ph505; UAS-let-7-SP cells collected from adults retained tumour formation in the hosts (Fig. 3c), indicating that let-7 is necessary to mediate the suppression of tumorigenic growth of ph505 cells.

It mediates the suppression of the NF-κB, JNK, p38 and Wnt pathways in a manner that depends on its deubiquitinating activity (reviewed in [1]).

A smaller segment of the C-terminus stretching from residues 1956 to 2301 is deleted in the su(wsp 1 allele, suggesting that this region is required to mediate the suppression of pigmentation seen in the wsp alleles.

Erk1/2/STAT6 pathway mediated the suppression on the anti-inflammatory and proendocytic features.