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This observation suggests that GIGANTEA could be mediating the repression of tuberization by LD in potato.
This result was consistent with Tcf3 mediating the repression of Nanog in ESCs (Cole et al., 2008) and suggests that Jarid2 may modulate Tcf3 activity.
Some portion of the C-terminal domain may be important for mediating the repression effects of sRNAs, and one model proposes that these domains may help to recruit the Hfq:sRNA complex [74,75].
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Coupled with biochemical data, these studies indicate that EZH2α and EZH2β are capable of forming distinct repressive complexes that mediate the repression of unique gene networks within a wide variety of biological processes already characterized for PRC2, including proliferation, migration and differentiation, among others [ 42].
In addition, investigations on the molecular function of Prdm14 have demonstrated that the factor interacts with the Polycomb Repressive Complex 2 (PRC2) to mediate the repression of diverse sets of genes via binding to H3K27me3, thereby ensuring a naïve ESC state.
The metabolic fate of this free iron is uncertain, but our results suggest that it can not mediate the repression of the Fur regulon under oxidative stress.
These results suggest that Eph receptor signalling mediates the repression of spine proliferation induced by climbing fibre activity in Purkinje cell proximal dendrites.
To explore if an excess of polyunsaturated fatty acids could mediate the repression of LXR-dependent ABCA1 transcription in the absence of LRP1, we incubated wild type SMCs with increasing concentrations of arachidonic acid.
Recent studies have also shown that CLF, an Arabidopsis homolog of E z), directly mediates the repression of AGAMOUS (AG) via H3K27 trimethylation and thus controls floral organogenesis [47], [48].
In particular, each mediates the repression of the same subset of outer membrane proteins (Guillier and Gottesman 2008).
Thus, it seems that cell-specific mechanisms mediate the repression of antiapoptotic genes by the GR translational isoforms.
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