Exact(2)
This scaffold appears to contribute, with the lipid membrane and the protein machinery, to the closing dynamics of the pore, in competition with other forces mediating the opening of the exocytotic channel.
These results support the participation of a tyrosine kinase of the Src family in the initial steps mediating the opening of Panx1 channels following P2X7R stimulation and in the transmission of calcium signals among astrocytes.
Similar(6)
CO mediates the opening of BK channels (Step 3) in the cell membrane, as well as in the ER and the mitochondria thereby allowing pooled stores of K+ to be expelled.
Degradation of occludin appears to mediate the opening of endothelial-endothelial TJs [ 41].
Glycine 99 interacts with isoleucine 292 to mediate the opening of the gate at the entrance of the binding pocket.
By recruiting HATs, TAZ mediates the opening of chromatin, thereby increasing Tbx-5 transcriptional activity [ 51], which may also occur during MSC osteogenesis.
Moreover, chitosan can mediate the opening of tight junctions between neighboring epithelial cells reversibly, facilitating the paracellular transport of drug molecules ultimately leading to improved bioavailability of the drugs [ 29].
Moreover, chitosan can mediate the opening of tight junctions between epithelial cells reversibly, facilitating the paracellular transport of drug molecules ultimately leading to improved bioavailability of the drugs [ 29].
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