Sentence examples for mediating the inflammatory from inspiring English sources

PGE2 signals through four G-protein-coupled receptors, including the EP2 receptor that has been investigated for its role in mediating the inflammatory and phagocytic responses to Aβ [4].

Realization of the important role played by UA as a signaling molecule mediating the inflammatory effects of hyperuricemia in adipocytes and leukocytes, as well as in signaling to cancer cells (Figure 3) has emphasized the relevance of managing UA therapeutically which could significantly improve treatment strategies for cancer that is associated with hyperuricemic disorders.

Together suggesting CD28, through either CD80 or CD86 is capable of mediating the inflammatory response and lethality of polymicrobial sepsis.

Binding of NF-κB to DNA promotes the transcription of genes involved in mediating the inflammatory (TNFα) and fibrotic (collagens) responses to silica in mice [10] [12].

We have previously shown that B. burgdorferi expresses ligands for integrin α3β1 [27] and that integrin α3β1 is important for mediating the inflammatory response to B. burgdorferi [28].

It has previously been reported that integrin α3β1 may play an important role in mediating the inflammatory response to B. burgdorferi in human chondrocyte cell cultures [28].

TLR-4 pathway mediates the inflammatory response but not bacterial elimination in E. coli pneumonia.

Incorporating ASCs also mediated the inflammatory response and promoted a more constructive macrophage phenotype.

Dong, Y. et al. HMGB1 protein does not mediate the inflammatory response in spontaneous spinal cord regeneration: a hint for CNS regeneration.

Inflammatory cytokines mediate the inflammatory response (IL-1, IL-2, IL-6, IL-8, TNFα) and play a crucial role in the pathogenesis of OHSS.

Pivotal role in atherogenesis is played by macrophages, which are early site for lipid accumulation and mediate the inflammatory and immune response in the intima.