Sentence examples for mediating the functions from inspiring English sources

Signal Transducer and Activator of Transcription (STAT) 3 is activated in response to cytokines and growth factors and it has been recently identified as a novel signal transducer for TrkA, mediating the functions of NGF in nervous system.

Together, our findings suggest that Pak2 is the primary effector for mediating the functions of Rac and Cdc42 in T cell development and activation.

Paradoxically, papers from Jablons's group suggest that an inhibitor of apoptosis family protein, Survivin, may play a role in mediating the functions of Wnt/β-catenin pathway in apoptosis [ 27, 30, 31].

We have found a widespread role for FGF signaling in regulating the expression of genes mediating the function of the Spemann organizer.

Thus, besides the roles in regulating microgametogenesis and pollen tube guidance, AtPV42a and AtPV42b might also play a role in mediating the function of SnRK1 complexes in post-fertilization processes, such as seed development.

Argonaute proteins are important for mediating the function of miRNAs.

We then validated the effects of ADCY5 on mediating the function of miR-17 in senescence.

Previous studies demonstrated that MAPK and PI3K pathways are involved in mediating the function of a neudesin, a mouse homologue of GIG47.

The role of these eRNAs in mediating the function of the enhancer in directing basal gene expression was demonstrated in a recent study for the distal enhancer of the gonadotropin hormone α-subunit gene (Pnueli et al. 2015).

Instead of a Cactus (IκBα) kinase, D. melanogaster IKKε regulates F-actin assembly by mediating the function of non-apoptotic caspases via the degradation of DIAP1 but does not participate in NF-κB activation.

Histone deacetylases have been shown to be involved in oncogenic transformation by mediating the function of transcription factors in certain forms of haematologic malignancies and possibly in the pathogenesis of solid tumours (Rosato and Grant, 2004).