Sentence examples for mediating the entry from inspiring English sources

Although the initial interaction of the pathogen with the host macrophage is considered a critical step in the pathogenesis of Mtb, the role of the receptors that play a role in mediating the entry of Mtb into macrophages and in transducing intracellular signals is very controversial and far from being understood.

The CRAC channels are hexameric plasma membrane proteins mediating the entry of extracellular Ca2+ when the intracellular Ca2+ stores are depleted.

In this way, we have provisionally identified the protein carriers mediating the entry, into yeast, of 18 of 26 drugs studied.

We elucidated the mechanism mediating the entry of both choline and albitiazolium into P. falciparum-infected erythrocytes and into the intracellular parasite.

Upregulation of caveolar proteins and intercellular adhesion molecules indicate their possible role along with gp41 protein from HIV in mediating the entry of the pathogens by breaching blood-brain barrier.

The function of HA can be compared to that of gp120, as gp120 is also known to play a crucial role in mediating the entry of the virus into the host cell [ 1, 27].

Flow cytometric analysis showed that MP-g-OEI copolymers could efficiently mediate the entry of nucleic acids into cells.

EBOV preferably utilizes hTIM-1, not other TIM proteins, to mediate the entry efficiently, which suggests that hTIM-1 probably has a direct or indirect interaction with EBOV glycoprotein (GP).

The interaction of gp120 and co-receptor (CCR5/CXCR4) mediates the entry of HIV-1 into host cells, which has been increasingly exploited in recent years as the target for new antiviral agents.

Furthermore, SR-B1 was shown to mediate the entry of hepatitis C virus (HCV) in an HDL-dependent manner [21], [22], while it also plays an important role in the infection of hepatocytes by the malaria parasite [23].

Several endocytic mechanisms have been described to mediate the entry of material into the cells [ 24].