Sentence examples for mediating the commitment from inspiring English sources
Cdks are serine/threonine kinases that work in complexes with different types of cyclins to phosphorylate the retinoblastoma family of tumour suppressor proteins (pRB) mediating the commitment of the cells to enter cell cycle in response to external stimuli (reviewed in Ortega et al, 2002).
Our studies confirm that in the early stages of skin development, ΔNp63 proteins predominate and are hence likely to mediate the commitment of ectodermal cells to an epidermal cell fate.
For example, in Xenopus and zebrafish embryos primordial germ cells (PGCs) are specified by germ plasm that is inherited from the egg; in mice, Blimp1 expression in the epiblast mediates the commitment of cells to the germ line.
Besides phenotypic similarities between erythrocytes and thrombocytes found in nonmammalian vertebrates, this includes the common progenitors of these cells (TEPs/MEPs), similarities between EPO and TPO signaling, and shared signaling mechanisms mediating the lineage commitment.
These data support the hypothesis that sensitivity to IFN-γ decreases with increasing osteoclast differentiation and that the mechanism by which RANKL and IFN-γ reciprocally inhibit each other in pre-osteoclasts is mediating the irreversible commitment into the osteoclast or activated macrophage lineages.
Given ZEB1's involvement in mediating the expression of early adipogenic commitment factors, we next tested whether ZEB1 also regulates adipogenesis in uncommitted precursors such as the C3H10T1/2 MSCs.
The university has been mediating the dispute.
It's about mediating the journey".
It's been involved in mediating the Nagorno-Karabakh conflict.
Organizational Commitment mediated the indirect effects of Perceived Organizational Support on Turnover Intention (standardized estimate = −0.48) and on Provision of Medication Information (standardized estimate = 0.20).
As it was no longer significant when including affective organizational commitment in the regression, affective organizational commitment fully mediated the effect of organizational pride in employees' efforts on organizational proactivity.
