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Our results suggest that the fimG and fimH gene products are components of type 1 fimbriae and that FimH may be the tip adhesin mediating the binding of type 1 fimbriated E. coli to D-mannose residues on mucosal surfaces.
Grafting a polymeric coating onto GNP surface has the role of mediating the binding of drug molecules and, equally important, to provide stability of the particles in biological media.
Do conformationally- favored heavy atoms play any role in mediating the binding affinity?
These peptides were then synthesized and covalently conjugated to aminated microwells, modifying the surface and mediating the binding of β-gal through specific peptide-enzyme interactions (Figure 1a).
As mentioned above, the contacted residues Glu11 and Asn62 played a key role in mediating the binding affinity and orientation (Table 2).
The full length protein was shown to bind erythrocytes in a culture supernatant based erythrocyte binding assay [31] and the domain (region II) responsible for mediating the binding has been identified and characterized [8].
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A TF contains one or more DNA-binding domains (DBDs), which bind specific DNA sequences to mediate the binding of RNA polymerase at the onset of transcription initiation.
FKBP39, a Drosophila homolog, can bind the immunosuppressive drug FK506 and mediate the binding of the target element of JH and showed a dynamic upregulation from 3 hpi to 24 hpi [76].
It remains to be established if the same determinants mediate the binding of other kinesin adaptors (including syntaphilin) or, alternatively, they bind to other regions.
Water molecules that mediate the binding are shown as small red spheres.
CDC37 is a co-chaperone that mediates the binding of over 350 client proteins to HSP90β, including over 190 kinases190
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mediating the impact
mediating the inhibition
mediating the effect
mediating the semantization
mediating the dispute
mediating the function
mediating the inflammation
mediating the activation
mediating the failure
mediating the journey
mediating the building
mediating the conflict
mediating the production
mediating the initiation
mediating the response
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