Sentence examples for mediating the adverse from inspiring English sources

The converging effects of stress on the dynorphin kappa opioid system in the BLA and its key role in mediating the adverse effects of stress implies that new therapeutic strategies should be directed toward the development of KOR antagonists.

The findings of this study are, therefore, highly suggestive of the maternal pituitary-adrenal axis playing a central role in mediating the adverse effects of the low protein diet and this would be consistent with widely held views [31].

The hexosamine biosynthesis pathway (HBP) flux and protein O-linked N-acetyl-glucosamine (O-GlcNAc) levels have been implicated in mediating the adverse effects of diabetes in the cardiovascular system.

The major role of ICER in mediating the adverse effects of oxidised LDL led us to seek the mechanism responsible for its induction.

Here, we sought to further our understanding of the mechanisms mediating the adverse effects of the LH by studying DNA methylation, an epigenetic mark found to be altered in individuals with psychiatric disorders (e.g. [ 14, 32– 32]).

There is strong evidence that increased arterial stiffness and left ventricular hypertrophy and fibrosis, rather than atherosclerotic disease, mediate the adverse cardiovascular effects of CKD.

Drawing from theoretical assertions tested among adults with chronic pain, this study aimed to determine whether pain-related self-efficacy mediates the adverse influence of pain-related fear on functional outcomes in a sample of youth with chronic headache.

Further studies to elucidate the mechanisms that mediate the adverse effects of eugenol are necessary.

Inflammation and oxidative stress mediate the adverse cardiovascular effects of air pollution exposure (Brook et al. 2010).

One interpretation of this discrepancy is that RyR-independent mechanisms mediate the adverse effects of BDE-47 on the developing nervous system.

It has been proposed that epigenetic modifications such as DNA methylation may mediate the adverse developmental consequences associated with smoking during pregnancy (11).