Sentence examples for mediating t from inspiring English sources

A time course study in EAE found evidence of two step process mediating T cell and macrophage infiltration [11].

IL-12 is secreted by mature DCs and is involved in mediating T cell stimulation, while IL-10 is a potent inhibitor of DC activities.

Consistent with its important role in mediating T cell:APC interactions, LFA-1 is also required for subsequent T cell activation and proliferation [2].

The observed consensus pathways of T cell development, including requirements for ZAP-70, LAT, SLP-76, and Vav1, appear to reflect the restriction by Cbl of an otherwise much broader set of molecular pathways capable of mediating T cell development.

In summary, we found that stress significantly attenuates the spinal GRP system regulating male reproductive function, reducing expression of both GRP and the ARs mediating T effects on the system, interfering with male reproductive function.

The addition of 1400W, an iNOS inhibitor, or a neutralizing monoclonal antibody to TNFα resulted in a partial but significant release from inhibition indicating that both these molecules are involved in mediating T cell inhibition (Figure 5C).

Other monoclonal antibodies that may be used for GVHD act by blocking receptors involved in mediating T-cell activation.

In mammals, IFN-γ, together with LPS, are principal inducers for expression of CXCL9, -10 and -11 in neutrophils, thereby mediating T-lymphocyte recruitment via the CXCR3 (for review [57]).

These data strongly suggested an ATM-p53-independent pathway mediating T-cell apoptosis in RA.

We suggest that CXCR4 expression in T cells plays an important role in mediating T-cell recruitment to inflamed sites.

Maturation is the gene expression programme that renders DC capable of mediating T-cell expansion and activation (Steinman, 2008).