Sentence examples for mediating steps of from inspiring English sources

This is consistent with a key role of T3S effectors in mediating steps of the biology of C. pneumoniae that are conserved in human and animal strains, such as inclusion and intracellular development.

However, the enzymes mediating step three and four of the pathway were not predicted in the genome of R. litoralis and also the aminotransferase responsible for the last step of the pathway, i.e. the degradation of 4-aminobutyrate to succinate-semialdehyde, was also not identified.

Through these multimolecular complexes, several tetraspanins are thought to mediate steps of the metastatic cascade.

The intermediate steps of signal transduction pathways mediating these changes are unknown.

Atg7 belongs to the ubiquitin like conjugation system (E1-like enzyme) mediating early steps of phagophore formation.

This results in gene expression changes that are crucial for mediating early steps of reprogramming from epithelial to mesenchymal identity including downregulation of classical epithelial and cell cycle genes as well as upregulation of mesenchymal markers (Postigo et al, 2003; Kowanetz et al, 2004; Barrallo-Gimeno & Nieto, 2005).

Finally, comparative gene array analysis of these cell lines offers the first step in identifying factors that mediate specific steps of the cardiac specification program.

CsA differentially inhibited signaling pathways which mediated distinct steps of the angiogenic process.

The second Mg2+ cation, which is coordinated in the vicinity of the α-phosphate, remains bound within the active site to mediate later steps of catalysis.

The major integrins and respective ligands that mediate these steps of EPC function will be discussed in detail in the present review.

There is a body of evidence that α4-integrin can mediate several steps of leukocyte recruitment cascade (i.e., rolling and adhesion) through α4-integrin/MADCAM-1 (mucosal addressin cell adhesion molecule-1) and α4-integrin/VCAM-1 pathways.