Sentence examples for mediating stem from inspiring English sources

Moreover, knock-down of glucose transporter 3 in ESCs impaired the beating function of ESC-derived cardiomyocytes, suggesting its potential role in mediating stem cell differentiation.

The chemokine SDF-1α plays a critical role in mediating stem cell response to injury and disease and has specifically been shown to mobilize neural progenitor/stem cells (NPSCs) towards sites of neural injury.

These results demonstrate the critical role of RAGE in mediating stem cell survival and highlight the importance of the RAGE ligand axis in ADSC therapy for diabetes.

Elucidation of the molecular pathways mediating stem cell SCS expression is a crucial step towards improving our understanding of the secreted factor profile and its clinical utility [ 204].

The Notch-1 receptor with a role in maintaining stem cell pools and mediating stem cell fate is also considered a MSC marker [ 30, 31].

Ubiquitin-mediated protein degradation plays a variety of roles in the regulation of many developmental processes, including mediating stem cell division through degradation of cell cycle regulators.

To address these questions and further elucidate the factors that mediate stem cell function, we undertook an analysis to identify genes whose expression is correlated to Oct4.

Recently, our group demonstrated that P-cadherin expression is able to mediate stem cell properties in basal-like breast cancer cells [ 30].

To determine whether exposure to anti-tumor T cell activity mediates stem-like functional properties, we took advantage of recent evidence suggesting that stem-like glioma cells are depleted by the Shh antagonist, cyclopamine [33].

We had recently demonstrated the important role of miR-132 in mediating the stem cells induced post-infarct revascularization [ 55].

Wang et al. previously reported the p38 pathway plays an important role in mediating hematopoietic stem cell senescence induced by IR, and it can be activated by oxidative stress, and pharmacological inhibition of p38 can effectively abate IR-induced residual BM injury [ 32, 33].