Sentence examples for mediating spore entry from inspiring English sources

This is not surprising considering that the cellular receptors mediating spore entry into these two types of cells are almost certain to be distinct.

However, prior to this study little information was available regarding the molecular mechanism of spore-epithelium interactions, what factors mediate spore entry into epithelial cells or the biological consequence of disrupting the entry process.

The results from the transwell assays indicate that inhibition of Src-mediated spore entry dramatically reduced B. anthracis dissemination through epithelial cells.

Therefore, we investigated the connection between PI3K and c-Src in mediating spore uptake by epithelial cells.

These results suggest that both the side chain length and presence of a charge at Ssp4 residue 36 may be important for mediating spore resistance properties.

Over expression of exogenous wide-type p85α did not increase spore internalization, possibly because the amount of endogenous adaptors was sufficient to mediate spore internalization (Fig. 2, E and Fig. S1, D).

We tested if spore entry into epithelial cells was mediated by a class IA PI3K.

These results indicated that specific components on B. anthracis spores were necessary and sufficient to induce spore entry into non-phagocytic cells.

In this study we sought to determine the molecular events involved in spore entry into lung epithelial cells.

SU6656 at a concentration of 50 µM significantly inhibited spore entry into A549 cells by approximately 70% (data not shown).

These results suggested that both PI3K and c-Src are involved in regulating actin polymerization during spore entry.