Exact(2)
An explanation for this may be that additional cellular factors present in COS7 are responsible for mediating sequestration of DND1 and APOBEC3.
This case strongly supports the hypothesis that parasite surface proteins such as PfEMP1, A-type RIFIN or STEVOR are involved in interactions of infected erythrocytes with endothelial receptors mediating sequestration of mature asexual and immature sexual stages of P. falciparum.
Similar(58)
In the mechanical hypothesis, specific interactions between iRBCs and vascular endothelium are thought to mediate sequestration of iRBCs within the brain resulting in removal from peripheral circulation [ 19- 21].
We have previously shown that the sense (GGGGCC n RNA forms a G-quadruplex structure [ 11], which could mediate sequestration of proteins.
Paradoxically, we propose that Caprin-2 inhibits translation of the AVP mRNA, perhaps by displacing ribosomes or by slowing initiation or elongation, or through mediating sequestration into translationally inert storage or transport granules.
Under this scenario, MBNL2-dependent suppression of GFP CUG) 91 mRNA-induced toxicity would be mediated by MBNL2-mediated sequestration of CUG repeat RNA, rather than the other way around as traditionally understood.
Pro-inflammatory cytokines upregulate cell adhesion receptors (e.g., intercellular adhesion molecule-1 [ICAM-1]) that mediate sequestration of parasitized erythrocytes in brain microvasculature, leading to vessel occlusion [16] and blood-brain barrier dysfunction [17].
Autophagy (or more specifically macroautophagy) is a process that mediates sequestration of macromolecules and organelles into specialized cytosolic vesicles for subsequent delivery and degradation in lysosomes (1– 3).
Phosphorylation of YAP1 at S127 by NDR mediates sequestration of YAP1 in the cytoplasm, restricts the transcriptional coactivator function of YAP1, and suppresses proliferation of human colon cancer cells.
Furthermore, PfEMP1 mediates sequestration of infected RBC aggregates in the microvasculature of various organs and is thus directly responsible for severe outcomes, including cerebral and placental malaria (MacPherson et al., 1985; Pongponratn et al., 1991; Baruch et al., 1996; Gardner et al., 1996; Reeder et al., 1999; Beeson and Duffy, 2005).
Following the identification of the genes for xylem Cd transport in A. thaliana and A. halleri, OsHMA3 has been identified as a regulator for xylem Cd transport in rice by mediating vacuolar sequestration of Cd in root cells (Miyadate et al. 2011; Ueno et al. 2010).
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