Sentence examples for mediating risk from inspiring English sources
Genome-wide association studies in autoimmune and inflammatory diseases (AID) have uncovered hundreds of loci mediating risk.
While these analyses clearly demonstrate the overall enrichment of disease risk alleles on gene regulatory regions, they are not designed to identify individual regulatory regions mediating risk or the genes under their control, and thus uncover the specific molecular events driving disease risk.
Our data do not statistically support a joint effect between IRF4 and sun sensitivity in mediating risk for NHL.
These data indicate that impulsivity is a behavioral endophenotype mediating risk for stimulant dependence that may be exacerbated by chronic drug exposure, whereas abnormal sensation-seeking is more likely to be an effect of stimulant drug abuse.
Schalkwyk et al. (45) found evidence for allele-specific methylation in this region supporting the theory that this region could be imprinted and mediating risk via an interaction between genetic and epigenetic factors.
Our findings support the hypothesis that factors involved in fetal growth and body size regulation, specifically components of the IGF axis, play a role in mediating risk of childhood ALL.
Posttraumatic stress disorder (PTSD) and problem drinking are common and often co-occurring sequelae experienced by women survivors of adult sexual assault, yet revictimization may mediate risk of symptoms over time.
This suggests that the regions implicated by MSP may be more likely to mediate risk for narrower diagnostic models tested across GWLS.
There is a need for experimental research designs that enable disentanglement of inherited genetic from environmentally mediated risk effects.
Chronic inflammation may mediate risk of colorectal cancer (CRC); however, the association between circulating inflammatory markers and risk of CRC has been inconsistent.
This syndrome thus represents the most common genetic alteration known to mediate risk of schizophrenia (Bassett and Chow 2008), and one of the most penetrant causes of schizophrenia.
