Sentence examples for mediating proliferation of from inspiring English sources

Amphiregulin mediates self-renewal in stem cell-like mammary epithelial cells [80], and has been implicated in epithelial remodeling in asthma, with elevated serum levels immediately following asthma attacks and in mediating proliferation of human bronchial epithelium [81].

Biochemical, genetic, and gene expression studies in mouse models and in vitro epithelial cell lines have, in recent years, provided insights towards understanding both the roles of Wnt signaling in mediating proliferation of intestinal stem cell populations [ 13, 14], and of Wnt and Notch signaling in the differentiation of secretory populations [ 15- 17].

This suggests that oestrogen may mediate proliferation of hPASMCs and may contribute to PAH pathology.

We propose that Brk, like other tyrosine kinases, signals downstream to STAT5b to mediate proliferation of breast cancer cells.

These structures expressed Hoxa10 (homeobox A10), a transcription factor that mediates proliferation of stromal tissue prior to implantation.

16α-Hydroxyoestrone (but not two or four hydroxyoestrogen) mediates proliferation of hPASMCs, an effect which is exaggerated in cells from PAH patients.

In addition to a prognostic role, the specificity for ARPC1B-containing Arp2/3 complex uncovered here might provide the basis for future development of small molecule inhibitors, which would specifically target the molecular machinery mediating proliferation and dissemination of tumour cells.

In addition, AIB1 interacts with several signalling molecules mediating proliferation, survival and migration of cells, including human epidermal growth factor receptor 2 (HER2) [ 7].

Lan et al. found that HGF can mediate proliferation and migration of primary dopaminergic nerve progenitor cells separated from the placenta [ 23].

Another constituent, NAC, suppressed the expression of NF-kB mediated proliferation genes, such as c-FLIP, Cyclin D and Bcl2 through the inhibition of IKK activity [ 27].

In turn, IQGAP1 activates b-Raf and mediates proliferation of endothelial cells.