Your English writing platform
Discover LudwigSuggestions(4)
Exact(4)
In this study, we focused on the role of such post-transcriptional gene regulation in females in mediating postmating responses.
In addition, we identified sexually dimorphic dsx circuitry within the abdominal ganglion (Abg) critical for mediating postmating responses.
Using an intersectional Flippase-recombinase approach to manipulate subsets of dsx neurons, we uncovered downstream dsx neuronal elements associated with this dsx+/ fru+/ ppk+ uterine sensory cluster in the CNS involved in mediating postmating responses.
We found a subpopulation of dsx-Abg neurons sending two bilateral fascicles along the abdominal nerve trunks that ramify on the uterus and vaginal plates, suggesting that dsx neurons might play a role downstream of the SP-sensory neurons in mediating postmating responses.
Similar(56)
A SP-responsive G protein-coupled receptor for SP-mediated postmating responses has been identified; females lacking this sex peptide receptor (SPR) remain receptive, exhibiting virgin-like behaviors, postmating [ 51].
Many of the striking postmating responses of females to mating are mediated by the effects of these Sfps (Chapman 2001; Gillot 2003; Ram and Wolfner 2007a; Wolfner 2009).
SPR is broadly expressed in the CNS and reproductive tract ([ 13] and Figure S3) and is required for SP-mediated postmating behavioral responses, as females lacking SPR remain receptive, exhibiting virgin-like behaviors, even after mating or SP injection [ 13].
That dsx-Abg neurons also project, and form presynaptic arborizations on the uterus, and that the effects on postmating responses when their function is impaired again argue that these neurons play a direct role in mediating processes such as egg fertilization and oviposition.
Postmating responses were restored in Df(1 SPR; UAS-SPR dsx Gal4 mated females.
This suggests they are promising candidates for involvement in the regulation of female postmating responses.
► dsx circuitry plays a pivotal role in the female postmating switch ► Peripheral dsx neurons detect and respond to sex peptide ► Central dsx neurons convey this signal to higher-order processing and direct postmating responses.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com