Sentence examples for mediating pain from inspiring English sources

Only by understanding the molecular circuits complexity and the substances mediating pain, the development of increasingly specific tools for the identification of new markers, will be possible.

Tetrahydrocannabinol, or THC, the plant's main psychoactive ingredient, binds to a class of receptors on neurons that are involved in mediating pain, appetite, and mood, among other things.

It has been suggested that persistent hypothalamic activation could be the factor that contributes to generate a central permissive state which predisposes to activation of the trigeminal system, mediating pain, and of the parasympathetic reflex, producing the autonomic symptoms [52].

TS of sensory neuronal responses to nociceptive stimuli is a form of central plasticity that shifts the sensory information from tactile to nociceptive before transmitting the nociceptive information to brain areas mediating pain sensation.

Mast cells trigger inflammation that is associated with local pain, but the mechanisms mediating pain are unclear.

Functional imaging has notably contributed to delineating the functional anatomy of the brain network mediating pain responses [4].

Prospectively, we have shown that painful OA leads to depressed mood through the mediating effects of pain on fatigue and disability[ 10].

In fact, we noted that depression levels observed in our sample of CTTH patients were low; therefore, it is possible that the mediating effect between pain interference and the emotional burden of headache may be different in individuals experiencing higher levels of depression.

To assess for potential mediating effects of pain catastrophizing on outcomes, the PCS and WOMAC scales will be administered one week prior to and 1 week following TKA.

The findings of the present study add to the large body of evidence demonstrating the importance of alterations in VGSC activity in mediating different chronic pain states and therefore advocates the continued development and evaluation of novel sodium channel blocking drugs for the treatment of OA pain.

A bootstrapped multiple mediation analysis was used to examine the mediating role of patients' pain intensity and opioid craving in the association between NA and prescription opioid misuse.