Our results show that Stx2-induced placental toxicity and fetus mortality is mediated by an increase in NO production.
Our results reveal that Stx2-induced placental damage and fetus mortality is mediated by an increase in NO production and that AG is able to completely reverse the Stx2 damages in placental tissues, but not to prevent premature delivery, thus suggesting other mechanisms not yet determined could be involved.
We aimed to examine whether smoking-associated postoperative mortality is mediated through smoking-associated postoperative complications in patients who were current smokers at the time of their surgery.
12 To our knowledge, no previous studies have assessed to what degree the increased smoking-associated postoperative mortality is mediated by specific complications associated with smoking.
While smoking is the main cause of lung cancer, some of the smoking related mortality is mediated through IHD and some, like COPD was in the current study classified to mortality amenable through health care.
Our findings tend to favor an explanation that, at least in the early period after bereavement, the increase in mortality is mediated through acute or short-term events, with all older people being vulnerable, irrespective of pre-existing comorbid conditions.
16 17 In this study, we aimed to examine whether smoking-associated postoperative mortality is mediated through smoking-associated postoperative complications in patients who are current smokers at the time of their surgery.
In conclusion, this study found that a high proportion of association between smoking and postoperative 6-month and 1-year mortality is mediated by postoperative complications, especially pulmonary complications.
In the present study, we examined whether the association of plasma ADMA with mortality is mediated by FGF-23, however, from our results we conclude that the association between ADMA and all-cause mortality is independent of plasma intact FGF-23 in RTR.
The multivariate model was also performed without including hypertension as a potential confounder because some investigators suggest that the potential beneficial effect of water hardness on IHD mortality or stroke mortality is mediated through the reduction of hypertension (Chakraborti et al. 2002; Griffith et al. 1999; Hopps and Feder 1986; Laurant and Touyz 2000; Peacock et al. 1999).
