Sentence examples for mediating its interaction from inspiring English sources

Hspabp, thought to be a tumor suppressor, is important for Hsp70 function by mediating its interaction with Hsp90 [86].

For example, we showed that the C-terminal region of zfPOT1 was responsible for mediating its interaction with zfTPP1.

TG2 contributes to the organization of the extracellular matrix via binding to fibronectin and mediating its interaction with collagen and integrins [10], [14], [15].

These data suggest that the GPRIII and GPRIV motifs of AGS3 play a major role in mediating its interaction with USP9x.

To summarize, these data revealed that the proline-rich domain of Foxp3 is essential in mediating its interaction with UXT.

Importantly, these preformed structural elements in TC-1 are involved in mediating its interaction with Cby (18).

Filament binding rate constants are important for not only understanding how Arp2/3 complex works with type I NPFs like WASP/N-WASP, but also how other regulators control Arp2/3 complex activity by mediating its interactions with filaments.

FAF1 is a 74-kDa protein with an N-terminal domain that mediates its interaction with Fas, the Fas-interacting domain (FID), and a functional ubiquitin-like C-terminal domain that is required for its pro-apoptotic activity.

If Sir2 is not sumoylated, it is presumable that some sumoylated proteins may mediate its interaction with other proteins such as Esc2 and regulate its activity.

To identify the domain(s) on HDAC6 that mediates its interaction with CLIP-170, plasmids that express various truncated forms of HDAC6 were transfected together with GFP-CLIP-170.

The SH3 domain of CAS mediates its interaction with several proteins involved in signaling pathways such as focal adhesion kinase (FAK), tyrosine phosphatases PTP1B and PTP-PEST, and the guanine nucleotide exchange factor C3G.