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In the SARS virus, this protein binds to a receptor on the surface of human cells mediating its entry.
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HCV virions are bound to lipoproteins, called "lipoviroparticles," wherein the circulating virus hides and mediates its entry into the hepatocytes through lipoprotein receptors [ 13].
We previously observed that cFΦR4 fails to enter cells at 4 °C or in the presence of sodium azide, suggesting that energy-dependent endocytic processes mediate its cell entry.
The HIV-1 co-receptor CCR5 possesses sulfo-tyrosine (TYS) residues at its N-terminus (Nt) that are required for binding HIV-1 gp120 and mediating viral entry.
Influenza virus surface glycoprotein, hemagglutinin, holds a critical role in mediating viral entry into host cell.
We reported previously that a small molecule named CL-385319 could inhibit H5N1 influenza virus infection by targeting hemagglutinin, the envelope protein mediating virus entry.
Moreover, stress response genes and virulence genes mediating enhanced entry into macrophages (enhA/B/C) were also induced under late infection (TP) and PE conditions.
This is not surprising considering that the cellular receptors mediating spore entry into these two types of cells are almost certain to be distinct.
This ubiquitylation precedes Aurora-A activation, which also occurs before mitosis, and is required for mediating mitotic entry.
If the Kapβ2 RAM interaction is mediating nuclear entry, then inhibiting Kapβ2 expression should reduce RAM nuclear localization.
The data in the present study do not delineate the molecular transporters mediating Ca2+ entry into the mitochondria.
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