Sentence examples for mediating its effect from inspiring English sources

These in silico data, together with our findings of reduced migration of MPNST cells in the presence of higher levels of miR-29c, argue that miR-29c acts as a tumour suppressor gene in MPNST and mediates it effect through modifying tumour migration by mediating its effect through both collagens and MMP2.

As shown in Fig. 1C, diazoxide did not inhibit glucose-mediated activation of PDE3B, indicating that glucose is not mediating its effect via endogenously produced insulin.

TGF-beta1, an anti-inflammatory cytokine, is upregulated following LPS stimulation, mediating its effect through SMAD family proteins.

SIAH2 appears to have several mechanisms of mediating its effect.

This observation suggests that Limk2 interacts with PlexinA1 in mediating its effect in semaphorin signalling.

Since HH signaling is received by mesenchymal cells, what is mediating its effect on NKX2-1?

It is possible that NFAT-133 may be mediating its effects through some of these pathways since the compound did not significantly activate PPAR-γ.

To understand how Gal-3 could be mediating its effects, we analyzed C. neoformans gene expression in its presence and absence.

These data indicate that UCH L1 might be mediating its effects on migration via the AKT pathway.

It is therefore most probable that dp12 is affecting factors other than CXCL12 in mediating its effects on tumour growth.

Thus, it is possible that glucose mediates its effect on PDE3B via a cAMP-dependent mechanism [38].