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Finally, childhood sexual abuse did not demonstrate mediating influences on any of our outcomes.
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Empirical examples of the analysis of a teacher student group illustrate the applicability of the methods used in investigating the mediating influence of context on collaborative activity.
It may thus be possible that age has a moderating and/or mediating influence on the relation between endophenotype and phenotype.
While the importance of SES as a predisposing or mediating influence on drug use might be more established in general population studies, it may be less relevant in the older age group because of a lower rate of psychological distress and greater access to income security plans and retirement pensions that prevent extreme poverty.
We also find enzymes can mediate large influences on distant metabolites or enzymes.
The effects of glucocorticosteroid on the behavior of H. influenzae in mice may also be mediated by influences on the host as well as by direct effects on the bacterium.
Indeed, epidemiological studies of diabetes and many other complex diseases have begun to consider the role of genetic imprinting and more generally how epigenetic modification can mediate environmental influences on gene expression [ 52].
Studies from one of our laboratories demonstrated that in mice, global genetic deletion of the inhibitory G protein Gαi2 (which mediates muscarinic influences on the heart) is associated with a reduced vERP, a prolonged corrected QT interval (QTc), and a predisposition to VT.
Taken together with our results, this suggests that dopamine might be mediating social influence on object value.
Our data further highlight that the pathways mediating SEP influences on risk factor emergence are nonlinear and complex (22).
This latter observation accords with a causal role for the amygdala in mediating modulatory influences on sensory cortices [Amaral, 2003; Armony et al., 1998; LeDoux, 1996; Phelps and LeDoux, 2005].
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CEO of Professional Science Editing for Scientists @ prosciediting.com