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COX-2 is an inducible enzyme mediating inflammatory responses.
In this review, we discuss the role of eicosanoid biosynthetic pathways in mediating inflammatory responses during bacterial infection using experimental Lyme arthritis as a model system.
Factors mediating inflammatory responses outside the CNS likely play critical roles in CNS dysfunction.
JAMs have additionally been demonstrated to interact with leukocytes and be involved in mediating inflammatory responses [ 30, 31].
They play important roles in mediating inflammatory responses, recruiting inflammatory cells to sites of tissue damage or contributing to resisting the invasion of various pathogens.
Intracellular activation of caspase 1 and phosphorylation of PKCϵ, enzymes involved in the signalling pathways mediating inflammatory responses, were under investigation.
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Of note, the role of miR-155 in mediating inflammatory response has been multifaceted.
Transcription factors, particularly NF-κB, AP-1 and Nrf2, are signaling molecules with vital roles in mediating inflammatory response, cellular proliferation and either antioxidative or detoxification systems.
One of the most widely investigated pattern recognition molecules is TLR4 usually mediating inflammatory response to gram negative lipopolysaccharide particles (LPS); however, TLR4 activation is significantly enhanced by oxidative stress occurring during IR injury [ 59].
Collectively, these findings demonstrate that high IL-28A levels in the lung effectively suppress the development of Th2 and Th17 cell mediated inflammatory responses and Th2-mediated allergic airway disease.
TM (10 mg/kg) has significantly reduced the LPS mediated inflammatory responses.
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mediating behavioral responses
mediating cellular responses
mediating automatic responses
mediating hypoxic responses
mediating inflammatory processes
mediating misleading responses
mediating osteoclast responses
mediating inflammatory genes
mediating immune responses
mediating divergent responses
mediating postmating responses
mediating inflammatory attacks
mediating apoptotic responses
mediating proinflammatory responses
mediating inflammatory events
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