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Results highlighted the prominent role of interferons in mediating inflammatory processes in asthmatics, and further supported the finding that GCs mediate their activities by repressing the interferon pathway.
iNOS is an important enzyme for mediating inflammatory processes.
In the past decade, they have been shown to have promising therapeutic potential in mediating inflammatory processes.
In addition to iNOS, COX-2, which is an inducible and isoform enzyme in inflammatory cells [ 38], is another vital enzyme for mediating inflammatory processes.
Several genes mediating inflammatory processes were also highly up-regulated, such as the chemokine receptor CCR5, and the glycoprotein CD74.
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COX-1 is constitutively expressed in almost all tissues [12]; COX-2 is the inducible form of the enzyme, which is expressed in response to inflammatory stimuli and growth factors and is involved in mediating pain and inflammatory processes [13], [14].
Statins have been shown to have promising therapeutic potential in mediating anti-inflammatory processes in animal model studies as well as clinical trials of rheumatoid arthritis, autoimmune encephalomyelitis, inflammatory colitis and psoriasis.
A recent study in streptozotocin-induced diabetes in rats showed overexpression of iNOS in the diabetic liver and kidney, suggesting a potential role for iNOS in mediating organ dysfunction [ 44]. iNOS may also mediate insulin resistance in inflammatory processes, impairing insulin signaling and worsening hyperglycemia.
"There may be 50 different inflammatory processes going on," Dr. Remick went on.
Although the causes of schizophrenia are unknown, inflammatory processes have already been implicated in it.
Cancer often involves inflammatory processes.
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mediating crucial processes
mediating cognitive processes
mediating inflammatory attacks
mediating cellular processes
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mediating inflammatory reactions
mediating signalling processes
mediating healing processes
mediating physiological processes
mediating evolutionary processes
mediating inflammatory events
mediating inflammatory signals
mediating inflammatory effects
mediating such processes
mediating key processes
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