Sentence examples for mediating inflammatory pathways from inspiring English sources
Notably, most of the previously reported HMGA1 transcriptional targets include NFκB regulatory elements in their promoter regions and many participate in mediating inflammatory pathways [[ 16], Resar and Sumter unpublished data].
25 27 Considering their well-described roles in mediating inflammatory pathways and smooth muscle contractility, we hypothesized that PROK1, via PROKR1, may be important in regulating events leading to the onset of parturition.
The overall lack of benefits for anti-inflammatory-based therapies in AD may reflect the activation of multiple and complex signaling pathways mediating inflammatory reactivity.
Intracellular activation of caspase 1 and phosphorylation of PKCϵ, enzymes involved in the signalling pathways mediating inflammatory responses, were under investigation.
Novel physiological functions of PXR have been discovered including regulation of NF- κB-mediated inflammatory pathway, vitamin D metabolism, cholesterol and lipid homoeostasis, energy homoeostasis, apoptosis as well as cell proliferation (reviewed in Zhou et al, 2009).
In this review, we discuss the role of eicosanoid biosynthetic pathways in mediating inflammatory responses during bacterial infection using experimental Lyme arthritis as a model system.
Our results suggest that by focusing on common urothelial β-AR mediated inflammatory signaling pathways, reasonable pathophysiological mechanisms and potential therapeutic strategies could be developed for chronic inflammatory diseases like IC.
Mori, T. et al. IL-1 beta and TNF alpha-initiated IL-6-STAT3 pathway is critical in mediating inflammatory cytokines and RANKL expression in inflammatory arthritis.
Hence, it is crucial to study these alternate pathways and their role in mediating inflammatory arthritis.
Therefore, immune cells depend on ROS to not only kill phagocytosed pathogens directly, but also to mediate inflammatory and immune signaling pathways [ 36].
When activated mast cells undergo degranulation they release a substantial amount of enzymes that mediate several inflammatory pathways.
