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Kourrich, S., Glasgow, S. D., Caruana, D. A. & Chapman, C. A. Postsynaptic signals mediating induction of long-term synaptic depression in the entorhinal cortex.
In addition to mediating induction of various pro-inflammatory genes in innate immune cells, NF-κB regulates the activation, differentiation and effector function of inflammatory T cells.15,16 Recent evidence suggests that NF-κB also has a role in regulating the activation of inflammasomes.17 Not surprisingly, deregulated NF-κB activation is a hallmark of chronic inflammatory diseases.
To investigate the relative importance of COX1 and COX2 activities in mediating induction of UCP1 expression in such cells, we treated Rb−/− adipocytes with isoproterenol/9-cis retinoic acid in the absence and presence of selective COX1 and COX2 inhibitors.
We therefore investigated the involvement of these two pathways in mediating induction of SOCS3 by flavone.
Genetic evidence suggests a crucial role for the noncanonical NF-κB pathway in mediating induction of GM-CSF in Th17 cells [ 55].
To confirm the role of the CIP2A/PP2A/p-Akt pathway in mediating induction of apoptosis of HCC cells by TD52, we generated PCL5 cells with ectopic overexpression of myc-tagged CIP2A by transient transfection.
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Western blot analysis indicated that heat shock mediated induction of endogenous Hsp90 expression was not inhibited in GFP positive tadpoles (Fig. 4C).
p75NTR stimulates calpain activation through its Chopper cell death domain, [11] and mediates NGF-induced inhibition of GSK-3β [12]; in addition, it can mediate induction of cell death through the activation of JNK [13].
Direct Chlamydia-endothelial cell interactions are known to mediate induction of VEGF [ 37].
NF-κB is a transcription factor that mediates induction of genes by TNF in many cell types, including OCPs [ 38].
This includes the prnA gene that encodes the regulatory protein that mediates induction of the whole cluster by proline.
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