Sentence examples for mediating gene transfer from inspiring English sources

The key limitation of nonviral vector approaches has been their lack of efficiency in mediating gene transfer and transgene expression in the airway epithelium.

We, and others, have previously shown that AAV vectors are more efficient at mediating gene transfer in males compared with females in rodents and canine models.

Consequently, ISs are considered as major players of genome evolution and plasticity, mediating gene transfers and promoting genome duplication, deletion and rearrangement [ 7].

The potential of the vector to mediate gene transfer in CHO cells was investigated.

Toward achieving this goal, we have identified a novel heptameric peptide (YTYQGKL) that functions as a localization moiety to mediate gene transfer in murine DCs.

In this study, we compared the transfection effectiveness of liposomes with the new transfection reagent FuGene 6 in bovine sperm mediated gene transfer (SMGT).

In conclusion, we were able to show effectiveness of sperm mediated gene transfer is significantly affected by choice of transfection reagent and by plasmid architecture.

In addition, Agrobacterium rhizogenesis mediated gene transfer technique was employed to generate hairy roots and to enhance the production of tropane alkaloids in the studied medicinal plant.

Further, the results indicate that Coulombic interactions between the histidine residues modulate protonation and subsequent conformational transitions required for peptide mediated gene transfer activity and are an important factor to consider in future peptide design.

In this study we compare the ability of self-inactivating Human Immunodeficiency Virus 1 (HIV-1) and Equine Infectious Anaemia Virus (EIAV -based vEIAV -basedediate gene transfer to rabbit and human corneas and to a murine corneal endothelial cell line.

Ex vivo, retrovirally mediated gene transfer into hematopoietic progenitor cells has been shown to provide sustained correction of two forms of SCID, that is, SCID-X1 and adenosine deaminase deficiencies.