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We provide evidence and mechanistic insight that CXCR7 acts as specific scavenger for CXCL12 and CXCL11 mediating effective ligand internalization and targeting of the chemokine cargo for degradation.
Here, we characterized an important role for the Bcl-2 member NOXA in mediating effective drug combinations, even if the single drugs induced NOXA-independent cell death.
Application of DCM to animal local-field potential data has facilitated validation studies, where independent, invasive measurements (e.g. microdialysis or pharmacological perturbations) suggest that DCM can be used to estimate the physiological mechanisms responsible for mediating effective connectivity [ 40 ].
As ROS are essential for initiating proinflammatory cytokine production and adaptive immune maturation, the generation of these highly reactive molecules should be regarded as a necessary proinflammatory-derived third signal for mediating effective adaptive immune activation.
The CD4+ T cells were functionally competent, mediating effective allogeneic responses that involved polyclonal TCR Vβs.
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We have, however, shown that the AF C system has an insufficient capacity to mediate effective C-mediated tumour cell killing.
This chapter focuses on providing information for the design of constructs that mediate effective silencing.
The chapter also provides the first evidence that Cre recombinase can mediate effective site-specific deletion of transgenes in zebrafish.
Although the interaction of tetramers is diffusion controlled, it is strongly driven by their geometry to mediate effective subunit targeting.
It also elaborates on the photochemistry, physical properties and release mechanisms of photosensitizers entrapped within optimized liposomes that mediate effective PDT treatments.
FA-PPI mediated effective transfection of the TNF-related apoptosis-inducing ligand gene (TRAIL) in human hepatoma Bel 7402 cells, leading to cell apoptosis and great suppression of cell viability.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com