Sentence examples for mediating different pathways from inspiring English sources

In this work we analyze the regulatory interactions mediating different pathways of endoderm induction by identifying co-regulated transcription factors.

Recent studies have shown that attachment of polyubiquitin chains on target proteins linked via lysine-48 of ubiquitin typically leads to degradation by the 26S proteasome [ 6], whereas linkage via lysine-63 mediates different pathways such as internalization of membrane proteins, activation of signal transduction and DNA damage repair [ 7].

This suggests that SIRT1 possibly mediates different repair pathways via modulation of repair proteins in a mutually exclusive way.

Experimental studies have suggested that overexpression of different growth factor receptors in breast cancer mediates different cell signaling pathways and makes the cancer cells become less responsive to treatment.

Based on our results, LOV1 is likely an additional upstream regulator that may mediate different a signalling pathway to CO (Figures 3 and 4).

The development of BPD may be mediated through different pathways, involving diverse risk factor profiles.

QST measures of modalities conveyed within the same tract were significantly (P<.05) correlated (|r|=.46 .84) in patients with SCI, but not in controls, whereas those modalities mediated by different pathways had lower and generally nonsignificant correlations (|r|=.05 .44) in both patients and controls.

Presumably as a result of the differences in their structural, biophysical and biochemical characteristics, the various mutants have been reported to have different cytotoxic effects, and this cytotoxicity to be mediated by different pathways (reviewed in [24]).

Our data showing that atorvastatin inhibits JNK phosphorylation/activation in septic rats indicate that the beneficial effect of this drug in improving survival and reducing insulin resistance is mediated by different pathways.

The post-exponential down regulation of Rot was still observed in the clpX mutant, indicating that the effect of ClpX and RNAIII on Rot expression is mediated by different pathways.

It is possible that GH release is mediated via different pathways to behavioural effects.