These data suggest that NTN1, signaling though NEO1, maintains the integrity of the end bud by mediating contacts between cap and luminal epithelial cells, and these contacts are required for robust forward growth of the mammary tree.
The binding of these ligands to CCR4 helps to guide Tregs towards DC, mediates contact between these two cell types and thus inhibits activation of DC and the DC-mediated T cell response.
A heterodimer may mediate contact between two CIK cells and two tumor cells at most.
Another feature of HEAT repeats is the presence of conserved polar residues near the surface inter-helix loop, which mediate contact between the two helices [13].
Anti-CD3 × anti-HER2 BsAb is designed to mediate contact between cytotoxic T cells and tumor cells expressing high levels of HER2; thus, anti-CD3 × anti-HER2 dimers are the ideal effectors.
We identified 8 homologs of Cellulose-Binding Elicitor Lectin (CBEL), a cell surface glycoprotein that plays a role in adhesion to host wall components [ 50], as well as a Class II hydrophobic protein which mediates contact and communication between the fungus and its environment [ 51].
These results suggest that hemagglutinins mediate contact between bacterial cells impairing X. fastidiosa movement in the plant xylem and thus reducing virulence [8].
PfEMP-1 molecules are concentrated on knob-like protrusions that mediate contact between parasitized RBCs and MVECs or monocytes [14], [27].
We wanted to evaluate the differences between water mediated contacts at protein-DNA interfaces in protein∶DNA complexes (single proteins bound to DNA) and in protein∶protein∶DNA complexes (multiple proteins bound to DNA).
A major group of genes altered in Cr VI) transformed cells were genes related to cell junction, a type of specialized structure mediating the contact between cells or between cells and extracellular matrix.
