Exact(2)
Given the importance of SH3 domain adaptors in mediating connections between proteins at adhesion sites [37] we undertook a human proteome-wide SH3 domain phage-display screen using the cytoplasmic domain of β-DG as an affinity ligand, in order to identify potential adaptor proteins.
Whole brain data will be acquired and analysed for derivation of fractional anisotropy measures of white matter integrity and tractography of selected axonal tracts mediating connections between limbic and frontal regions of interest.
Similar(58)
Finally, vaccinating individuals with large betweenness centrality (frequency of mediating connection between pairs of individuals along the shortest paths) is superior to vaccinating ones with large connectedness to others or randomly chosen individuals, which was suggested by previous model studies.
Provincial hubs provide structure within the local community, and connector hubs mediate connections between multiple communities.
SMA appears to mediate connections between language areas in the PT brain.
CAMSAPs mediate connections between microtubule minus ends and adhesion proteins at epithelial adherens junctions (Meng et al., 2008), and the synaptic-localized CAMSAPs we observed may play a similar bridging role at synaptic adhesion sites.
We will evaluate whether, over months and years, stress-related alterations of HPA-axis function and inflammation mediate connections between URT and declines in cognitive performance.
Central actors are often seen as experts and most sought after for advice within the network while brokers can bridge or mediate connections between unlinked members.
The mediator complex is involved in transcriptional regulation by mediating the connection between transcription factors and the RNA polymerase II initiation complex 4. MED12 comprises a subunit of a CDK8 submodule of the Mediator, which also contains MED13 and Cyclin C, and regulates the kinase activity of CDK8 5, 6.
More remains to be understood about the mechanisms mediating the connection between amphetamine and crime, but the elevated risk of relapsing into crime may have important implications for follow-up and treatment of primary amphetamine users.
Skelemin, also known as myomesin-1.1 and originally identified as a muscle M-line cytoskeletal protein of 185 kDa, is expressed primarily in embryonic heart and has been shown to play a critical role in mediating the connection between ECM and cytoskeleton during the early stages of cell spreading.
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