Sentence examples similar to mediating class from inspiring English sources

Activation-induced deaminase (AID) is a DNA-mutating enzyme that mediates class-switch recombination as well as somatic hypermutation of antibody genes in B cells.

Additional supporting information may be found in the online version of this article at the publisher's web-site Activation-induced deaminase (AID) mediates class-switch recombination (CSR) and somatic hypermutation (SHM) of immunoglobulin genes in GC B cells.

Histone deacetylation in response to phosphorylated MEF-2D can be mediated by class I or class II HDACs (Gruffat et al. 2002).

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We do however now mention in the Discussion (p. 23) that BLyS mediates class switching, and the corresponding reference cited specifically states that TACI and BAFF-R are involved in antibody isotype switching.

Interestingly, all interactions proposed by the Bayesian model of Chen et al were mediated through class 1 ligands and of the consensus sequence X-S/T-X-Φ-COOH (Fig. S5).

It may be that the availability of a transnational gay identity so clearly mediated by class, can itself be homogenizing and limiting.

Sequential deacetylation events mediated by class I/II HDACs and Sirt1, however, target FoxO to transcribe genes needed for cell cycle arrest and survival responses to environmental stress [ 38].

Addition of 3-MA effectively prevented ShhN-elicited LC3 elevation (Fig. 4B; supplementary material Fig. S1D), indicating that Shh-induced autophagy in hippocampal neurons is possibly mediated through class III Ptdlns3K.

In addition to Akt-induced phosphorylation, Foxo1 is acetylated by histone acetyltransferases (HATs) such as CREB-binding protein (CBP /P300; Foxo1 deacetylation is mediated by class I III deacetylases, including the nicotin amide adenine dinucleotide (NAD -dependent histoNAD -dependent (histoneSirt1 (Accili andeacetylase04).

In theory, processing and presentation of exogenous intact antigens via endocytosis favors loading of the major histocompatibility complex (MHC) class II pocket, thus mediating clonal expansion of class II restricted tumor-reactive CD4+ T-helper lymphocytes.