Sentence examples for mediating cellular response from inspiring English sources

The results suggest that the bioactive Hap phase might play an important role in mediating cellular response to the composites.

Thus, tumor suppressor pathways, such as the RB and p53 pathways, are critical for mediating cellular response to both exogenous and endogenous stress signals, and inactivation of these pathways paves the way for cancer development.

Loss of RB and p53 has lead to enhanced tumor susceptibility in various cell types and mouse models in response to DNA damaging agents, demonstrating the importance of RB and p53 in mediating cellular response to exogenous stress [49], [50], [51].

Together these findings highlight the importance of genomic uracil accumulation in mediating cellular response to pemetrexed.

Physical properties of the cellular microenvironment, such as rigidity and topography, also play critical roles in regulating cellular functions and mediating cellular response to a variety of stimuli, such as strain and shear stress.

Together, our findings reveal the critical role of the H3K4me3 interaction in mediating cellular responses to genotoxic stresses and offer new insight into the molecular mechanism underlying the tumor suppressive activity of ING1.

beta-Catenin, a key component in the canonical Wnt-signaling pathway, is activated in fibrotic processes and wound repair and, as such, could play a role in mediating cellular responses to irradiation.

H2O2 causes to release of Ca2+ flux into the cellular matrix, which is the control point for signal transduction processes or activates some members of the mitogen-activated protein kinase (MAPK) family-central for mediating cellular responses to stresses (Neill et al. 2002).

In addition, NF-κB is involved in mediating cellular responses to numerous environmental stressors.

G protein-coupled receptors (GPCRs) play central roles in mediating cellular responses to environmental signals leading to changes in cell physiology and behaviors, including cell migration.

The H subunit of Mg-chelatase (CHLH), a chloroplast protein, has also been proposed to be an ABA receptor involved in mediating cellular responses to ABA during seed germination, post-germination growth and stomatal movement [7].