Sentence examples for mediating cellular interactions from inspiring English sources
Due to the merit of sizes (a few micrometers), the spheres can be intercalated into cells, mediating cellular interactions in 3D cell-spheroid engineering, and also can stimulate osteogenic differentiation of cells when incorporated into cell-laden gels.
During trichome and root hair development additional R3 single repeat MYBs are important as negative regulators mediating cellular interactions during pattern formation [ 18- 24].
In addition, heterophilic adhesion molecule receptor ligand pairs including α4β1-integrin CD106 (VCAM-1) are expressed by FLSs and synovial macrophages, providing a means for mediating cellular interactions within the synovial lining layer [ 18].
Accordingly, very large groups of hypoxia induced genes are involved in mediating cellular interaction with the extracellular environment, which may point toward their involvement in angiogenesis, immune response, and signal transduction.
The syndecans, a family of cell-surface heparan sulphate proteoglycans, have been proposed to mediate cellular interactions with extracellular effector molecules, such as growth factors and components of the extracellular matrix, during critical phases of development.
The effect of stromal cell MHC-II deficiency on CD8+ T cell activation was rather unexpected as MHC-II molecules are not thought to mediate cellular interactions with CD8+ T cells.
The role of initiating anoikis comes down to proteins that mediate cellular interaction with the ECM and neighboring cells, such as integrins and E-cadherin.
Parts of the extracellular environment are extracellular matrix components, such as heparan sulfate (HS) proteoglycans, which mediate cellular interactions during development (Bernfield et al. 1999; Ramirez and Rifkin 2003).
DOI: http://dx.doi.org/10.7554/eLife.04433.011 As MHC-II molecules are not thought to directly mediate cellular interactions with CD8+ T cells, we reasoned that CD8+ T cell activation in the absence of lymph node stromal cell MHC-II expression could be an indirect effect of local CD4+ T cell activation.
Our observations identify a new role for syndecan-1 in mediating the cellular interactions and fate of positively charged submicrometer amorphous silica particles in the alveolar type II epithelial cell, a target cell for inhaled particles.
It has been suggested for Adam12, (another member of the Adam family of proteins), that the cysteine-rich domain plays a role in mediating the cellular interactions via syndecans and integrin [ 39], a similar role for this domain in Adam2 can be postulated.
