Sentence examples for mediating cell size from inspiring English sources

However, given the multiplicity of S6K targets [3], the role of rpS6 phosphorylation in mediating cell size control is not self-evident.

RhoBTB3 is a member of the RHOBTB subfamily of Rho GTPases that play a role in mediating cell size, proliferation, apoptosis, survival, polarity, call adhesion and membrane trafficking [36].

These results indicate that tsc2 mediates cell size rather than cell proliferation in the liver and spinal cord during embryogenesis.

Taken together, these data demonstrate that blocking mTORC1 mediates cell size reduction in the cells of all cell cycle phases and affects cell cycle regulation separable from its cell size effects.

YAP and Yorkie have recently been shown to be negatively regulated by the Hippo/MST pathway and play an important role in mediating cell contact inhibition, organ size and tumorigenesis [21], [22].

Fibronectin also mediates cell migration.

This study showed the close relationship between ribosome biogenesis and cell size, mediated by the transcription factor Sfp1.

In general, increasing cell size is mediated by mTOR, which suppresses autophagy.

We further demonstrated that the changes in muscle cell size induced by PLD were mediated by mTOR.

PDK1 plays an important role in mediating the effects of insulin and growth factors that regulate cell proliferation, cell size, differentiation and survival [10].

Rapamycin treatment of Akt1 structures prevented the increased cell size, overgrown, and filled structures, indicating that Raptor/mTOR signaling was mediating the effects of Akt1 in these cells [ 47].