Sentence examples for mediating cell proliferation from inspiring English sources

These are important molecules in mediating cell proliferation and play a role in the induction of anti-apoptosis mediators.

Moreover, miR-34a-5p regulathe the protective effect of sev-preconditioning in injured H9c2 cells by mediating cell proliferation and cell apoptosis.

These enzymes can be targeted to increase expression of tumor suppressors and impede activation of oncogenic signaling pathways mediating cell proliferation and tissue invasion.

Human epidermal growth factor receptor 2 (HER2) is a transmembrane glycoprotein that belongs to the family of epidermal growth factor receptor, mediating cell proliferation and differentiation in the developing embryo and in adult tissues (Cho HS et al., 2003).

This cell population was found to express high levels of survivin and telomerase, which are both important molecules in mediating cell proliferation.

These and other studies [11], [12] have provided evidence that Stat3 is required for both the initiation and promotion stages of chemical carcinogenesis by maintaining survival of DNA-damaged stem/progenitor cells and by mediating cell proliferation necessary for the clonal expansion of initiated cells.

A growth factor can mediate cell proliferation, survival or differentiation depending on the stage of CNS development and/or cell differentiation.

Next, the growth responses to 10nM E2 and 1µM 25HC were abolished by 10µM ICI (Fig. 4F and 4H), suggesting that ERα mediates cell proliferation induced upon exposure to both compounds.

These findings suggest that VEGF acts downstream Cx43 to mediate cell proliferation.

Moreover, ACTN4 can interact PI3K downstream kinase Akt to mediate cell proliferation [ 37 ].

Therefore, Fhit appears to be capable of suppressing Gq-PLCβ mediated cell proliferation.