Sentence examples for mediating cell killing from inspiring English sources

When rituximab binds to CD20 at the cell surface rituximab activates complement-dependent cytotoxicity and human Fc receptors, mediating cell killing through an antibody-dependent cellular toxicity.

Note that it is well known that NK cells are the only population within PBMCs mediating K562 cell killing.

In addition to ADCC, CDC is another mechanism by which therapeutic mAbs can mediate target cell killing.

By fixing complement or activating immune cells such as natural killer cells, macrophages, and T cells, antibodies can mediate additional cell killing against target cells.

As it returns to the ground state, there are two ways in which the energy released can mediate selective cell killing.

Soluble elotuzumab F ab′ 2 alone or in combination with lenalidomide failed to mediate myeloma cell killing (Fig.  3c) and induce certain NK cell activation markers (CD25 and CD54 expression) in the co-culture model examined (Fig.  3d).

Or the energy can be directly transferred to oxygen to form singlet oxygen (O2), a subset of reactive oxygen species, which then oxidizes various substrates (type II reaction) and thus mediates selective cell killing.

Therefore, our results indicate that irrespective of the effects of wild-type p53 on reovirus infection, p53 accumulation with Nutlin-3a treatment ultimately promotes reovirus-mediated cancer cell killing.

Based on our observation that NaD1 binds phosphoinositides through the same loop region, it is tempting to speculate that plants have evolved a suite of defensins that specifically interact through their β2 β3 loop regions with different membrane lipids to mediate fungal cell killing.

Normally, T cell receptor (TCR) ligation triggers the armed CD8+ T cells to mediate target cell killing.

Once bound, the immune cells become activated and mediate tumour cell killing via phagocytosis by macrophages or via the release of toxic granules from NK cells [ 101].