Sentence examples for mediating cell growth from inspiring English sources

These studies have demonstrated the dose dependent effects of selenium in mediating cell growth and death via modulating the Ca2+ release from the ER [25], [26].

Moreover, NF-κB activation is an important event mediating cell growth and survival, thus we analyzed NF-κB activity in KYSE180 cells transfected with NF-κB reporter plasmid which then treated with low doses of S100A14 for 8 h.

Many glycan intermediates at different loci along the pathways, not necessarily glycans at the termini, can be secreted out of the Golgi to the targeted sites where they perform biological functions, such as mediating cell growth and development, cell-cell communication, immune recognition/response, and molecular homeostasis [2], [7] [10], [14].

mTOR is a 289 kDa serine-threonine kinase partially downstream of Akt and is responsible for the complex integration of anabolic stimuli mediating cell growth [ 32].

These findings support the molecular mechanisms associated with overexpression of Kv10.1 in tumor pathogenesis and add Kv10.1 to the p53/miRNA34/E2F1 regulator pathway with Kv10.1 mediating cell growth.

Overall, there are several genes listed in Table 1, which are known to have functions mediating cell growth, apoptotsis, and tumorigenesis, showing expression profiles that are reasonable for theoretically elucidating the molecular mechanism mediating enhanced sensitivity to androgen withdrawal by overexpression of IL-6.

Akt serves as an intermediate signaling molecule for mTOR, which is a serine/threonine kinase that mediates cell growth, proliferation, survival, protein translation, and other oncogenic functions.

p110β has been shown to mediate cell growth and development, DNA replication, insulin sensitivity, tumorigenesis, and G-protein-coupled receptor-activated signaling (12- 15).

Activation of HER2 initiates a cascade of signal transduction, including PI3K/Akt and MAPK pathways, to mediate cell growth and survival [ 3].

Nevertheless, although mechanisms that regulate phosphofructokinase and pyruvate kinase for example have been shown to mediate cell growth and proliferation, whether regulatory mechanisms of GAPDH have functional roles in cell growth and proliferation related to aerobic glycolysis is not known.

However, in many of these tumors, the p53-family member TAp73 can still mediate cell growth arrest or apoptosis by regulating a set of target genes that overlaps with p53-responsive genes.