Sentence examples for mediating cell death from inspiring English sources

A family of cystein proteases, the caspases, plays a central role in mediating cell death.

The essential role of mitochondria in mediating cell death was indicated by robust translocation of cytochrome c from the mitochondria into the cytosol, 2.5- to 5-fold activation of caspase 9, severe disruption of mitochondrial inner membrane potential, and complete inhibition of apoptosis by the selective caspase 9 inhibitor.

Studies show that TG2 is a player in mediating cell death processes.

This may reflect the different biological pathways used by 5-FU and TNF-α for mediating cell death.

Mitochondria produce up to 90% of the cellular energy and also play a critical role in mediating cell death through the apoptotic pathway [16].

All fungal incompatibility gene systems-with the exception of the P. anserina het-s/het-S prion system-possess at least one constituent bearing a HET domain, suggesting that this domain might be involved in mediating cell death [23].

In the CNS, Ca2+ influx via receptor-mediated mechanisms reportedly mediates cell death [ 34].

A novel method of locally producing a desired endogenous agonist was through gancyclovir mediated cell death of glioma cells expressing thymidine kinase from adenovirus.

Herein, we report that AgNPs have notable anti-proliferative effect and induce apoptosis mediated cell death both in drug sensitive and in MDR cancer cells.

Dysregulation of ion homeostasis rapidly mediates cell death, forming the mechanistic basis by which a growing number of amphipathic but structurally unrelated compounds such as terpenoid phenols elicit antifungal activity (Zhang et al. 2012).

GAPDH can mediate cell death associated with oxidative stress [92].