Sentence examples for mediating cell apoptosis from inspiring English sources

IFIT2 has been reported to be a tumor suppressor via mediating cell apoptosis through activating caspase-3/7 activity.

By altering the levels and activities of transcription factors, activation of ERK pathway regulates the expression of various genes mediating cell apoptosis, proliferation and angiogenesis [ 19, 20].

These findings indicate that the SKA3/ DDX10 alterations may have potential roles in tumor development, and DDX10 may be involved in pathways mediating cell apoptosis.

Although BCL2L11 is well known to mediate cell apoptosis (Hagenbuchner et al., 2012; Luo and Rubinsztein, 2013; Dai and Grant, 2015), its expression pattern and the biological role in cancer have not been detailedly described yet.

OPN is well known in the literature as a survival factor that mediates cell apoptosis under certain pathological stresses.

STAT1 also mediates cell apoptosis by cisplatin in coordination with the cell-cycle regulator p53.

The second component is caspase-3, an executioner caspase that mediates cell apoptosis [ 28].

NF κB signaling can also engage the Caspase signaling pathway to mediate cell apoptosis.

Previous studies showed that the RGD peptide has the ability to mediate cell apoptosis [ 41], in which cell adhesion plays an important role.

Such increased level of Bax was not observed when cells were treated with TNF-alpha, which mediates cell apoptosis through death receptor rather than the mitochondrial pathway (data not shown).

BCL2L11 belongs to the BCL-2 family, and acts as a central regulator of the intrinsic apoptotic cascade and mediates cell apoptosis.