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CTLs play important roles in mediating cell adhesion and the recognition of pathogens in the immune system.
For bone tissue engineering, the ECM should also be considered in terms of its function in mediating cell adhesion to biomaterials.
Integrins are involved in a wide range of cell-to-extracellular matrix (ECM) and cell-to-cell interactions, mediating cell adhesion, signal transduction, tumorigenesis, tumor growth, and metastasis [1, 2].
FN and VN were adsorbed under non-competitive (single-protein solutions) and competitive (multi-protein solutions) conditions, and compared at different levels: adsorbed amount (radiolabelling), elution, functional presentation of cell-binding domains (ELISA), and role in mediating cell adhesion (antibody-based assay).
Apart from mediating cell adhesion, type I pili play a role in promoting cell invasion by a macropinocytosis-like process which involves both the host cell actin filaments and microtubules [17].
In mediating cell adhesion, syndecans form stable homodimers and bind to the heparin/heparan sulfate binding sites in the ECM with the HS chains and the cytoplasmic domains on core proteins interact with the cytoskeleton [30].
Similar(42)
Cell adhesion on the surface of such implants is necessary for better integration with the neighbouring tissue; however, hydrophobin surfaces do not mediate cell adhesion.
It has been shown to mediate cell adhesion through homophilic interaction and some data suggest association with the cytoskeleton [73].
Therefore, it was hypothesized that the RGD domain of OPN functionally mediates cell adhesion, migration and invasion through integrin engagement.
In contrast, MUC16 has also been demonstrated to mediate cell adhesion by binding to other cell surface glycoproteins such as galectin-1 and mesothelin [14], [15].
Therefore, the question of whether the RGD domain of tumor-derived OPN indeed mediates cell adhesion and migration has not been directly addressed.
More suggestions(15)
mediated cell adhesion
mediating cell fate
mediating cell binding
mediating pilus adhesion
mediating cell gradient
mediating cell differentiation
mediating cell invasion
mediating cell survival
mediating cell contact
mediating cell retention
mediating cell size
mediating firm adhesion
mediating monocyte adhesion
mediating cell behavior
mediating cell polarity
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