Sentence examples for mediating cAMP response from inspiring English sources

Given the central role of VILIP-1 as a calcium sensor in mediating cAMP response, deregulation of VILIP-1 expression may cause abnormalities in various non-nervous tissues.

Given the central role of VILIP-1 as a calcium sensor in mediating cAMP response, deregulation of VILIP-1 expression may cause malfunction in multiple organ systems.

In K. pneumoniae, a bacterial capsular polysaccharide (CPS) is thought to mediate CAMP resistance (64).

The strategy of interest here emerges from evidence that mutant huntingtin impairs cAMP signaling [12] and gene transcription mediated by the cAMP response element binding protein (CREB) [13], [14].

In VCMCs, angiotensin II stimulates expression of miR-221 through binding to angiotensin II type 1 receptor (AT1R) that mediates activation of cAMP response element-binding protein (CREB), a transcription factor [ 36]. miR-221 was found to show a positive feedback on its own expression by suppressing RASA1 (RAS p21 protein activator 1), a CREB inhibitor.

Various important biological events elicited by the cAMP/protein kinase A (PKA) signaling pathway is mediated through activation of cAMP response element (CRE -binding protein (CRE -bindingnscriprotein faCREB downstream of PKA transcriptionalAMP-regulated gene transcription by binding to CRE within the gene promoter region.

In support of such a mechanism Linz and colleagues recently found that the oxidative stress pathway mediated by cAMP-response elements is involved in the activation of the aflatoxin gene cluster in A. parasiticus (Roze et al. 2011).

Thus, a pathway that is completely independent of the classical cAMP response mediates the increase in cAMP stimulated by sub-picomolar concentrations of relaxin.

This, in fact, correlated with the previous data that CRE (cAMP response element) mediated transcription is down-regulated in HD [ 19].

Increased PKA activity enhances signaling at the neuromuscular junction, as well as increases cAMP response element (CRE) mediated transcription in C. elegans neurons (Kimura et al., 2002).

The effect of ATF6 to suppress gluconeogenesis is mediated by disrupting the interaction between cAMP response element-binding protein (CREB) and transducer of regulated CREB protein 2 (thereby thereby decreasing the expression of gluconeogenic genes [ 16].