Sentence examples for mediating association with from inspiring English sources

Recent data indicate that efficient nuclear import can involve the microtubule (MT)/dynein network, such that nuclear delivery of exogenous cargo could be enhanced by attachment to peptide modules mediating association with dynein components, but this has not been investigated.

These data suggest that TDP-43 can bind to TIA-1 at higher concentrations of TDP-43, such as with over-expression, but that binding to TIA-1 is not the predominant mechanism mediating association with SGs under basal levels of TDP-43 expression.

Thus fly APC2's Arm rpts can mediate association with Axin's middle region.

Alternative splice variants of TAF4 lack parts of the TAF homology domain, which mediates association with a variety of transcriptional factors.

SpnP possesses a structural feature that has only been previously observed in the related glycosyltransferase EryCIII, in which it mediates association with the auxiliary protein EryCII.

All five domains appear to function as protein interaction modules mediating associations of SAP scaffolds with their multiple interacting partners [11].

Here we report a cancer mutational hotspot in MLL3 within the region encoding its plant homeodomain (PHD) repeats and demonstrate that this domain mediates association of MLL3 with the histone H2A deubiquitinase and tumor suppressor BAP1.

The resulting fusion protein has no DNA binding motifs but possesses protein-protein interaction domains that are believed to mediate association with chromatin remodeling complexes.

The hGBPs are isoprenylated at their C-terminus via the CAAX domain, and the addition of this hydrophobic tag is thought to mediate association with membranous structures [21], [26], [36].

The p.L95F mutation is located in the conserved BTB domain of KLHL9, which mediates interaction with Cul3, while the Kelch repeats mediate association with substrates.

Our hypothesis predicted deleting either R2 or B should stabilize APC2 Axin interaction, by enabling APC2's Arm rpts to also productively mediate association with Axin.