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Some of these co-expressed genes are likely to be involved in mediating aspects of petaloidy.
Transgenic mice have demonstrated the importance of 11β-HSD1 in mediating aspects of the metabolic syndrome, as well as HPA axis control.
In contrast, the syndromes of PNFA and semantic dementia implicate dominant hemispheric dorsal fronto-insulo-parietal and anterior temporo-ventrofrontal networks mediating aspects of language output and comprehension, respectively (Saur et al., 2008; Seeley et al., 2009).
Recently, in vitro, in vivo, and clinical data have collectively demonstrated the importance of local cortisol generation via 11β-HSD1 in hepatic and adipose tissue in mediating aspects of the metabolic syndrome (3, 6).
In addition these results suggest the probable participation of these gene products in jasmonate signaling and redox homeostasis by mediating aspects of plant growth and biotic stress responses (Additional file 4).
By virtue of their expression patterns, the genes expressed in this cell type are candidates for mediating aspects of development or function of the symbiotic arbuscule-cortical cell interface.
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Overall, these studies demonstrate, through the use of novel transgenic mice, that IL1R1 on neurons and astrocytes differentially mediates aspects of sleep under physiological conditions and in response to central IL-1 administration.
(4) is1 is a potent pro-inflammatory cytokine, which mediates aspects of the "sickness behavior", a syndrome sharing similarities with major depression [33].
In mammals, almost all cells possess a single primary cilium that houses the Sonic Hedgehog pathway (Drummond, 2012) and mediates aspects of cell-cell signaling.
Previously, it had been found that the mammalian sirtuin SIRT1 is required to mediate aspects of the CR response in mice [ 14, 15].
However, because present data do not directly assess the functional importance of vHP ghrelin to LHA orexin neural circuitry in conditioned feeding, we acknowledge that this pathway might also mediate aspects of non-conditioned appetite and feeding behavior.
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