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Most games designed for educational or vocational use are designed for a very narrow purpose, mostly for mediating a small range of skills to a specific target group.
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Parents' disciplinary practices mediated a small share of the association between perceived material deprivation and children's behavior problems.
The presence of glutamate receptors was evidenced using symmetrical solutions such that at 0 mV, the addition of 100 µM glutamate mediated a small outward current, likely due to the presence of KOH in the internal solution (Fig. 2c), and at −70 mV the addition of glutamate mediated a large inward current, as K+ and Ca2+ ions flowed through open glutamate receptors (Fig. 2d).
However, CM from clone 7 mediated a small but significant increase in SDF-1 and CXCR4, while clone 21 gave a greater increase.
In contrast, at the A1-AR, each of the ligands mediated a small, ∼1.5-fold, increase in ABA-X-BY630 dissociation (Fig. 5 B).
However, invitation type did not predict attitudes towards screening but did predict knowledge (β = -.45, p =.001), which mediated a small effect of invitation type on intention (indirect β = -.06, p =.017).
However, at higher doses, TAM does not elicit a comparable gamut of responses as seen with higher doses of EE. Surprisingly, TAM increased luminal epithelial thickness [ 18], due to cellular hypertrophy and hyperplasia, that was not significantly different from EE, but mediated a smaller increase in luminal circumference with more endometrial glands compared to EE.
The majority of eIF4E-mediated Potyvirus resistances are mediated by a small number of amino acid changes in the eIF4E protein [31], [32].
Together with the ladder-like phylogenetic trees of EV-A7120, these factors suggest an evolutionary scenario of a proficiently host-adapted virus engaged in intense immune evasion mediated at a small number of virus particle surface sites that interact directly with the host immune system.
The recruitment of enolase by the RNA degradosome has been implicated in the turnover of certain transcripts, and it is mediated by a small segment of roughly a dozen residues that lie within a natively unstructured sub-domain of RNase E. Here, we present the crystal structure of enolase in complex with its recognition site from RNase E at 1.6 Å resolution.
On the basis of related studies, two broad categories of protein protein interfaces may be defined: ones in which ligand binding is mediated by a small subset of contact residues, and ones in which the free energy of binding arises from many productive interactions distributed over the entire protein protein interface.
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