Sentence examples for mediating a significant from inspiring English sources

Fogal et al [ 14] have recently reported that targeting surface nucleolin with an antibody preparation against nucleolin has no significant effect on tumor size or progression while mediating a significant reduction of blood vessel density.

Kunze et al (2012) reported that simultaneous siRNA-mediated knockdown of antiapoptotic protein mediated a significant reduction in cell viability and induction of apoptosis, suggesting Bcl-xL itself can be targeted for treatment.

Water bath presence mediated a significant increase in feeding behavior (Cornetto & Estevez, 2002), comfort behavior, and feed intake.

Immunoblot analysis from percoll-purified mitochondria further demonstrated that adenosine mediated a significant increase in mitochondrial PKCε but not PKCδ.

It was found that PP-PLLD-Arg/MMP-9 nanocomplex showed the photo-enhanced gene transfection efficiency in vitro, and could mediate a significant reduce of MMP-9 protein expression in HNE-1 cells.

(ii) In old rats, exercise mediated a significant increase of spontaneous locomotion in males.

In order to mediate a significant anti-tumor effect the fusion proteins must be able to reach the serum and remain stable for several hours.

However, it seems unlikely that microglia mediate a significant portion of 2MeSADP protection, since disruption of astrocyte mitochondrial function blocks protection.

By means of fluorimetric assay on regenerating muscle extracts, we showed that AVP did not, unlike TNF which mediated a significant increase in caspase activity, modulate caspase activity (Fig. 7A).

Sclerotization is a metabolic process, during which enzymes mediate a significant number of reactions.

Chronic low oxygen stress mediated a significant change only for the IGFBP1B ortholog.