A hallmark of memory CD8 T cells is long-term survival and ability to mediate a rapid recall response following rechallenge with the pathogen.
However during this process, a few cells develop into memory T cells that survive for extended periods of time and mediate a rapid and robust recall response following a subsequent infection by the same pathogen (reviewed in [3] [5].
Recently, members of the Chloride Channel (ClC) family were shown to mediate a rapid 2Cl−/H+ antiport reaction, indicating a close connection between transporters and channels in this protein family [43] [46].
We find that DosT and DevS mediate a rapid and sustained induction of the DevR regulon, respectively, in response to hypoxia achieved through the O2-scavenging and reducing property of AA.
When activated, TRPV1 mediates a rapid increase in axoplasmic Ca2+ [ 9, 64].
Immunofluorescence analysis revealed, that exposure to CXCL12 mediated a rapid cytoplasmatic clearance and translocation of CXCR4 in Huh7 and Hep3B (confirmatory data not shown) and in HT29.
As described above (Sect. Control of cell cycle progression by the Hog1 SAPK), Hog1 mediates a rapid, but transient, arrest of cell-cycle progression to allow adaptation.
Such transmission involves the release of a neurotransmitter from a pre-synaptic neurone and the subsequent activation of post-synaptically located receptors that mediate a rapid, phasic, electrical signal (the excitatory, or inhibitory, post-synaptic potential).
In addition, GC-1 cells express G protein coupled receptor 30 (GPR30), which mediates a rapid xenoestrogen-activated pathway in premeiotic germ cells, among which spermatogonia represent the most important cell population.
