Sentence examples for mediating a positive from inspiring English sources

Bem1 may induce cell polarization by mediating a positive feedback loop whereby Cdc24 is preferentially recruited/activated at the site of Cdc42GTP accumulation [19], [20], [21].

Similarly, upregulation of ppk1 encoding polyphosphate kinase increases polyphosphate levels and enhances activation of the MprAB two-component system [47], mediating a positive feedback loop through SigE [3].

In contrast to the suggested role in mediating a positive feedback at least in some cell lines, Rictor siRNA did not decrease phosphorylated AKT in the KLE cell line, although the siRNA decreased Rictor expression by 80%.

The IRF3/IRF7, NF-κB, and AP-1 bind to PRD I/III, PRD II, and PRD IV, respectively, where they promote the transcription of IFN-α, IFN-β, and pro-inflammatory cytokines (TNF, IL6, IL1β, etc).. Following production, IFN-α and IFN-β mediate a positive feedback-production loop by binding to the IFN-α/β receptor (IFNAR) in an auto- and/or paracrine manner.

The factors that mediate a positive correlation between ASP and MTV include spatial resolution and necrosis.

Elevated concentration of endothelin-1 mediateiate a positive response to inhaled nitric oxide.

It could be that the relationship with "the home" was reflected in the staff's body language who mediated a positive interest and engagement.

This active suppression by CTLA-4 expressing CTLA-4 expressinghe possibiliTr that cells4 engagement may mediate a positive signal foraiseslathey function.

Thus, Stat6 is likely to mediate a positive feedback loop in the progesterone response that is crucial for the delayed and sustained action of progesterone on breast cancer cells.

ROS have been shown to mediate a positive feedback on signal transduction elicited by, for example, PDGF, epidermal growth factor or nerve growth factor; this usually reinforces the receptor tyrosine kinases (RTKs) and involves p21Ras and Rac, leading to activation of a subunit of non-phagocytic NOX, likely a gp91phox analogue.

Although both Sfp1 and Sch9 mediate a TORC1 positive regulation of RIBI and RP genes, interaction of Sfp1 with TORC1 reduces Sch9 phosphorylation, resulting in a negative feedback loop (Lempiainen & Shore, 2009).