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In Guatemala, for example, where we have worked for a number of years, part of what we've ended up doing is mediating a number of the land conflicts.
The future development of polymer microparticles for genetic vaccine delivery is likely to evolve toward designing more sophisticated multi-component, multifunctional devices that are capable of mediating a number of cellular and molecular processes involved in the generation of immunity.
CREB's role in mediating a number of complex behaviours has been documented [ 33].
Furthermore, carbohydrates are known to play a pivotal role in mediating a number of biological processes.
Protein kinases regulate cell signalling pathways mediating a number of processes in cell proliferation, differentiation and survival (Gschwind et al, 2004).
NO has also long been considered to be a catabolic factor that contributes to the OA disease pathology by mediating a number of processes, including apoptosis, and perpetuating the expression of proinflammatory cytokines [ 1]. High concentrations of nitrites and nitrates have been found in the synovial fluid and plasma of patients with arthritis [ 2].
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Geranylgeranyltransferase and farnesyltransferase I, are noted to mediate a number of signal transduction cascades which are known to be involved in the causation of opioid withdrawal syndrome.
Although, α2C adrenergic receptor (AR) mediates a number of physiological functions in vivo and has great therapeutic potential, the absence of its crystal structure is a major difficulty in the activation mechanism studies and drug design endeavors.
Neutrophils, macrophages, and other inflammatory cells mediate a number of important cellular functions in injured tissue [33], [34].
Since SUMO modification participates in the regulation of multiple protein functions, repression of sumoylation may mediate a number of NO-related cellular events and pathological processes.
Hydrogen atoms mediate a number of important interactions and considering the energetic contribution associated with them is important in studies such as the analysis of ligand-protein and protein-protein interactions [5], [6], ligand screening [7], and structure-based drug design [8], [9].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com